Pentobarbital will lower the level or effect of darifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. pentobarbital will lessen the level or result of fosamprenavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. pentobarbital will lower the level or result of linagliptin by influencing hepatic/intestinal enzyme CYP3A4 ... https://phily568ohw0.livebloggs.com/profile