Tapentadol is partly metabolized via the hepatic enzymes CYP2C9, CYP2C19, and CYP2D6 so it innately has interactions with drugs that improve or repress the action/expression of one or more of such enzymes, and also with substrates of those enzymes (on account of Opposition to the enzyme); some enzyme mediators/substrates have https://motherb765yip5.wikimidpoint.com/user