New selective PAD4 inhibitors binding a calcium-deficient form of the PAD4 enzyme have validated the crucial enzymatic function of human and mouse PAD4 in both histone citrullination and neutrophil extracellular entice formation for, to our information, the first time. The therapeutic potential of PAD4 inhibitors can now be explored. Calculate https://leonardoy111kvg3.webbuzzfeed.com/profile